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MICE, INBRED MDX
Descriptors Found:
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DeCS
Descriptor
English
:
Mice, Inbred mdx
Descriptor
Spanish
:
Ratones Consanguíneos mdx
Descriptor
Portuguese
:
Camundongos Endogâmicos mdx
Tree Number:
B01.050.050.199.520.520.420.500
B01.050.150.900.649.865.635.505.500.400.420.500
B01.050.150.900.649.865.635.505.500.550.265
Definition
English
:
A strain of mice arising from a spontaneous
MUTATION
(mdx) in inbred C57BL mice. This
mutation
is X chromosome-linked and produces viable homozygous
animals
that lack the muscle protein
DYSTROPHIN
, have high serum levels of muscle
ENZYMES
, and possess histological lesions
similar
to human
MUSCULAR DYSTROPHY
. The histological features, linkage, and map position of mdx make these mice a worthy animal model of DUCHENNE
MUSCULAR DYSTROPHY.
Indexing Annotation
English
:
NIM with no qualifiers when experimental animal; check the tag MICE
See Related
English
:
Muscular Dystrophies
History Note
English
:
94
Allowable Qualifiers
English
:
AB
abnormalities
AH
anatomy & histology
BL
blood
CF
cerebrospinal fluid
CL
classification
EM
embryology
GE
genetics
GD
growth & development
IM
immunology
IN
injuries
ME
metabolism
MI
microbiology
PS
parasitology
PH
physiology
PX
psychology
SU
surgery
UR
urine
VI
virology
Record Number:
31309
Unique Identifier:
D018101
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
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